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Randomised trial, 1977

Does Bellergal help premenstrual syndrome?

Bellergal significantly improved fatigue, breast tenderness, nervousness, irritability, lethargy and listlessness. The study lacks details like sample size and duration.

Moderate study design Women with troublesome premenstrual syndrome symptoms

What they did

Placebo-controlled, randomized, double-blind, parallel group study in hospitals and general practice. Women with troublesome PMS received either Bellergal or placebo three times daily.

What they found

Bellergal significantly improved fatigue, tender breasts, nervousness, irritability, lethargy and listlessness. No side effects were reported.

What it means for you

Bellergal appears effective for several PMS symptoms without side effects. However, the abstract lacks important details: no sample size, duration, or explicit results comparing drug to placebo.

3x daily

Bellergal dosing frequency

About the study

Original title
Treatment of the premenstrual syndrome
Authors
Robinson K, Huntington KM, Wallace MG
Journal
British journal of obstetrics and gynaecology
Year
1977
Study design
Randomised trial
What was tested
Bellergal (belladonna alkaloids, ergotamine tartrate, phenobarbitone) three times daily

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