Review, 2000
What is GnRH and what is it used for in women?
GnRH is a hormone medication that stops the release of other hormones involved in ovulation. It is used to treat PMS, endometriosis, fibroids, and other conditions.
What they did
This is a clinical review article explaining how GnRH medications work and their uses in medical practice.
What they found
GnRH agonists initially stimulate hormone release, then suppress the pituitary-gonadal axis. GnRH antagonists directly suppress hormones without the initial stimulation. Both are useful for multiple clinical indications including endometriosis, fibroids, hirsutism, irregular bleeding, and premenstrual syndrome.
What it means for you
GnRH medications can be used for PMS when other treatments fail, but this is a review of how the medications work rather than evidence from a clinical trial. It does not describe specific benefits or side effects for PMS specifically.
1971
Year GnRH was identified and synthesized
About the study
- Original title
- A clinician's guide to the use of gonadotropin-releasing hormone analogues in women
- Authors
- Moghissi KS
- Journal
- Medscape women's health
- Year
- 2000
- Study design
- Review
- What was tested
- GnRH agonists and GnRH antagonists
- Read the paper
- https://pubmed.ncbi.nlm.nih.gov/10792849/
Topics
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