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Randomised trial, 1999

Does calcium reduce PMS symptoms?

Yes, this large study of 497 women found that calcium supplementation reduced PMS symptoms during the luteal and menstrual phases. This is strong evidence from a well-designed trial.

Strong study design 497 healthy women aged 18-45 (mean 33) in US, 80% white, with moderate or severe PMS

What they did

A randomized double-blind placebo-controlled trial at 12 US health centers. 497 healthy women aged 18-45 years (mean age 33, 80% white) with regular menstrual cycles and confirmed moderate or severe PMS symptoms were given calcium carbonate or placebo.

What they found

Calcium supplementation reduced PMS symptoms during the luteal and menstrual phases of the menstrual cycle. Women needed mood swings, depression, tension, anxiety, anger, or crying spells to qualify.

What it means for you

Calcium appears to be an effective supplement for PMS. The study was large and well-designed with 497 women. It was done in the United States primarily in white women, so results may vary in other populations.

497

Women studied

18-45 years

Age range of participants

mean 33 yrs

Mean age of participants

About the study

Original title
Calcium reduced PMS symptoms during the luteal phase of the menstrual cycle
Authors
Lynne S. Giddings
Journal
Evidence-Based Nursing
Year
1999
Study design
Randomised trial
What was tested
Calcium carbonate vs placebo
Open access
Yes

Topics