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Survey study, 2004

Does the body's stress response change during the menstrual cycle?

Yes. The body's stress response changes at different times in the menstrual cycle, with stronger responses during the second half of the cycle. Women show a different overall pattern than men.

Early or limited evidence 14 women tested at different points in their menstrual cycle, and 14 men as a comparison group.

What they did

14 women completed two mental stress tests at different points in their menstrual cycles. The same tests were given to 14 men, spaced the same number of days apart. Researchers measured heart rate, blood pressure, and how the heart's rhythm changes during stress.

What they found

During the second half of the menstrual cycle, the body's stress response system was more active compared to the first half. The calming response system was lower during the second half. Women overall showed different nervous system patterns than men, with more calming response and less stress activation. People rated the mental tasks as equally difficult regardless of cycle timing or gender.

What it means for you

The body's stress response changes predictably during the menstrual cycle, which may explain why some women feel more stress at certain times. This is a small study using a specific lab task, so results may not reflect stress responses during everyday life.

14

women tested

14

men tested

About the study

Original title
Cardiovascular reactivity to mental stress: relationship with menstrual cycle and gender
Authors
Sato N, Miyake S
Journal
Journal of physiological anthropology and applied human science
Year
2004
Study design
Survey study
Participants
14
What was tested
Mental stress tests (what was measured).
Open access
Yes

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