Randomised trial, 2017
Does lemon balm capsule or educational support work better for reducing PMS symptoms?
Yes, both lemon balm capsules and educational support programs significantly reduced physical, mental, and social PMS symptoms compared to placebo and no treatment. We can be fairly confident because this was a well-designed randomized controlled trial with 200 women tracked over 3 months.
What they did
Randomized placebo-controlled trial with 200 high school girls with PMS in four groups. One took 600 mg lemon balm daily for entire menstrual cycle for 3 consecutive cycles. One received educational support programs. One took placebo. One received no treatment. Researchers measured symptoms at baseline, 1 month, and 2 months after intervention.
What they found
All treatment groups showed significant reductions in physical, psychological, and social symptoms of PMS at all three measurement times. The control and placebo groups had the least improvement in symptoms over time, with much less change than the treatment groups.
What it means for you
For reducing PMS symptoms, both taking lemon balm supplements and receiving educational support about PMS appear to help. The study was large with 200 women and well-structured with multiple comparison groups. Main limitations are that it only included high school girls in one city in Iran, so results may not apply to all women or different age groups.
600 mg
Daily lemon balm dose
3 cycles
Duration of lemon balm treatment
200
Total number of girls studied
About the study
- Original title
- Comparison of the Effect of Melissa officinalis Capsule and Care Educational Programs on the Intensity of Physical, Mental and Social Symptoms of Premenstrual Syndrome in High School Female Students
- Authors
- Marzieh Akbarzadeh, Zeinab Moshfeghy, Mansureh Dehghani et al.
- Journal
- International Journal of Women s Health and Reproduction Sciences
- Year
- 2017
- Study design
- Randomised trial
- Participants
- 200
- What was tested
- Lemon balm capsule 600 mg daily for entire menstrual cycle for 3 consecutive cycles, or care educational programs
- Open access
- Yes
- Read the paper
- doi.org/10.15296/ijwhr.2018.05
Original abstract
Objectives: Premenstrual syndrome (PMS) is one of the psychosomatic problems related to women›s reproductive function, which is associated with emotional and mood symptoms such as anger, anxiety and irritability.The current study aimed to compare the effect of Melissa officinalis capsule and care educational programs on the intensity of physical, mental and social aspects of PMS in high school girls. Materials and Methods:This study was a randomized, placebo-controlled trial which was conducted on 200 high school girls with PMS who were randomly allocated into 4 groups in Shiraz.The first group received 600 mg of M. officinalis essence daily from the first to the end day of their menstrual cycle for 3 consecutive cycles; the second and third groups received care educational program and placebo respectively, and the last one was the control group.The data were analyzed using paired t test and Repeated measures analysis of variance (ANOVA). Results:The results of repeated measures ANOVA test revealed a significant reduction in 3 determined times, pre-intervention, one and 2 consecutive months after the intervention (P < 0.001), in the intensity of physical, psychological and social aspects of PMS symptoms, and this varied in different groups (P < 0.001).The extent of changes varied over time and in different groups, so, the control and placebo groups had the least symptom changes over the time Conclusion: Melissa officinalis capsule and care educational programs were much more effective in reduction of the severity of physical, mental and social symptoms of PMS compared to the control and placebo groups.
Reproduced under CC-BY.
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