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Randomised trial, 2014

Is chamomile as effective as mefenamic acid for breast pain associated with PMS?

Yes. Chamomile appeared to be similarly effective as mefenamic acid (a standard pain medicine) at reducing the intensity of breast pain associated with PMS.

Moderate study design 90 dormitory students in Iran with breast pain associated with PMS

What they did

Double-blind randomized trial from September 2011 to March 2012 with 90 dormitory students in Iran. Two groups of 45 received either chamomile capsules (100 mg) or mefenamic acid (250 mg) three times daily from day 21 of the menstrual cycle until the next menstruation.

What they found

Both groups showed a significant decrease in breast pain intensity. There was no significant difference between the chamomile and mefenamic acid groups.

What it means for you

Chamomile may work as well as a standard medicine for breast pain in PMS. The study only included dormitory students in one region of Iran, so it's unclear if results apply to other populations.

90

Students in study

100 mg

Chamomile dose

250 mg

Mefenamic acid dose

About the study

Original title
Comparison of the Effects of Matricaria chamomila (Chamomile) Extract and Mefenamic Acid on the Intensity of Mastalgia Associated With Premenstrual Syndrome
Authors
Farangis Sharifi, Masoumeh Simbar, Faraz Mojab et al.
Journal
Women’s Health Bulletin
Year
2014
Study design
Randomised trial
Participants
90
What was tested
Chamomile capsules (100 mg) or mefenamic acid (250 mg) three times daily from day 21 of cycle until next menstruation
Open access
Yes

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