Randomised trial, 2026
Can propolis and fennelin reduce PMS symptoms?
Yes, both propolis and fennelin reduced PMS symptom severity by about 79%, significantly better than placebo, but the study only lasted 2 menstrual cycles.
What they did
A double-blind, randomized controlled trial with 90 female university students. They were randomly assigned to propolis 500 mg (30 women), fennelin 30 mg extract (30 women), or placebo (30 women). Treatment lasted 2 menstrual cycles. PMS symptoms were measured using questionnaires.
What they found
Propolis reduced PMS symptom severity by 78.9% and fennelin by 79.3% (p = 0.016), both significantly better than placebo. Placebo showed no significant change (p = 0.206). No side effects were reported.
What it means for you
Propolis and fennelin may help reduce PMS symptoms in young women. The main limits are the short study duration (only 2 cycles), the young age of participants (university students), and small sample size, so results may not apply to older women with more severe PMS.
90
Women in study
78.9%
PMS symptom reduction with propolis
79.3%
PMS symptom reduction with fennelin
About the study
- Original title
- Comparison of the Effects of Propolis and Fennelin Capsules on Premenstrual Syndrome in Students: A Randomized Clinical Trial
- Authors
- Shayan A, Tiznobik A, Refaei M et al.
- Journal
- Reviews on recent clinical trials
- Year
- 2026
- Study design
- Randomised trial
- Participants
- 90
- What was tested
- Propolis 500 mg vs fennelin 30 mg extract vs placebo
- Read the paper
- doi.org/10.2174/0115748871406071251122055743
Topics
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