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Randomised trial, 2008

Does saffron help relieve PMS symptoms?

Yes, saffron at 30 mg daily was effective in reducing PMS symptoms including mood-related symptoms compared to placebo.

Moderate study design Women aged 20-45 with regular menstrual cycles and PMS symptoms for at least 6 months

What they did

Randomized, double-blind, placebo-controlled trial of women aged 20-45 with regular periods and PMS for at least 6 months. Women received either 30 mg daily saffron (15 mg twice daily) or placebo for 2 menstrual cycles. Main symptoms were measured daily and mood was assessed with the Hamilton Depression Rating Scale.

What they found

Saffron was significantly more effective than placebo in improving total premenstrual daily symptoms and depressive symptoms in cycles 3 and 4.

What it means for you

Saffron may be an option for PMS relief. However, the study abstract does not report the sample size, which limits assessment of how strong the evidence is. More research is needed.

30 mg/day

total daily saffron dose

15 mg

dose per administration

2

menstrual cycles tested

About the study

Original title
Crocus sativus L. (saffron) in the treatment of premenstrual syndrome: a double-blind, randomised and placebo-controlled trial
Authors
Agha-Hosseini M, Kashani L, Aleyaseen A et al.
Journal
BJOG : an international journal of obstetrics and gynaecology
Year
2008
Study design
Randomised trial
What was tested
Saffron 30 mg daily (15 mg twice daily)

Topics