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Non-randomised trial, 2017

What are the different types of PMDD according to traditional Chinese medicine?

The study identified two types of PMDD based on traditional Chinese medicine principles. Evidence is weak because the study did not use a randomized design.

Early or limited evidence Women with PMDD (exact number not specified)

What they did

Epidemiological investigation of women with PMDD to identify symptom patterns and subtypes using traditional Chinese medicine framework and statistical analysis.

What they found

Two subtypes of PMDD were identified. The first, called liver-qi invasion syndrome, involves excessive liver conveyance and dispersion. The second, called liver-qi depression syndrome, involves insufficient liver conveyance and dispersion.

What it means for you

This framework may help clinicians diagnose and treat PMDD differently depending on which subtype a woman has, according to traditional Chinese medicine principles. The findings were not tested in a randomized way, so evidence is limited.

2

Number of PMDD subtypes identified

About the study

Original title
Epidemiological Distribution and Subtype Analysis of Premenstrual Dysphoric Disorder Syndromes and Symptoms Based on TCM Theories
Authors
Qiao M, Sun P, Wang H et al.
Journal
BioMed research international
Year
2017
Study design
Non-randomised trial
What was tested
None - epidemiological classification study
Open access
Yes
Original abstract

We performed an epidemiological investigation of subjects with premenstrual dysphoric disorder (PMDD) to identify the clinical distribution of the major syndromes and symptoms. The pathogenesis of PMDD mainly involves the dysfunction of liver conveyance and dispersion. Excessive liver conveyance and dispersion are associated with liver-qi invasion syndrome, while insufficient liver conveyance and dispersion are expressed as liver-qi depression syndrome. Additionally, a nonconditional logistic regression was performed to analyze the symptomatic features of liver-qi invasion and liver-qi depression. As a result of this analysis, two subtypes of PMDD are proposed, namely, excessive liver conveyance and dispersion (liver-qi invasion syndrome) and insufficient liver conveyance and dispersion (liver-qi depression syndrome). Our findings provide an epidemiological foundation for the clinical diagnosis and treatment of PMDD based on the identification of different types.

Reproduced under CC-BY.

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