Skip to content

Case report, 2022

Can aripiprazole prevent menstrual psychosis?

In this case, a previously healthy adolescent girl experienced psychotic symptoms that appeared before her menstrual period and resolved when her period started. The medication aripiprazole prevented these episodes, but they returned when she stopped taking it.

Early or limited evidence One previously well adolescent girl.

What they did

Doctors described one previously well adolescent girl who experienced psychotic symptoms timed to the premenstrual phase of her menstrual cycle. A literature review of menstrual psychosis accompanied the case report.

What they found

The girl had psychotic symptoms in the days before menstruation, and they went away when her period began. These episodes stopped when she took aripiprazole but returned once she stopped the medication. This pattern suggests her psychosis was linked to her menstrual cycle.

What it means for you

This case suggests psychosis may link to menstrual cycle. When the girl stopped aripiprazole, her symptoms returned, showing the medication prevented episodes. A major limitation is that this is one adolescent girl, so we cannot know how common this pattern is or whether the medication helps others.

About the study

Original title
Menstrual psychosis
Authors
Ahern E, Cohen D, Prior C et al.
Journal
Irish journal of psychological medicine
Year
2022
Study design
Case report
What was tested
Aripiprazole (an antipsychotic medication).

Topics