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Randomised trial, 2000

What non-antidepressant treatments might help PMS?

A study of 466 women found calcium was effective at reducing emotional, behavioral, and physical PMS symptoms. Cognitive therapy, light therapy, and tryptophan also showed promise in early trials.

Moderate study design 466 women with premenstrual syndrome in the main cited study

What they did

This article reviewed multiple studies on non-antidepressant PMS treatments, including a large double-blind placebo-controlled study of 466 women who took calcium.

What they found

Calcium reduced emotional, behavioral, and physical premenstrual symptoms. Ovulation-suppressing medications helped but carried risks like low estrogen and bone loss. Cognitive therapy, light therapy, and tryptophan showed promise in preliminary trials.

What it means for you

Calcium may be a safe, accessible option to try for PMS. Several other non-drug treatments look promising but need more research before we know if they really work.

466

Women in calcium study

About the study

Original title
Non-antidepressant treatment of premenstrual syndrome
Authors
Pearlstein T, Steiner M
Journal
The Journal of clinical psychiatry
Year
2000
Study design
Randomised trial
Participants
466
What was tested
Calcium and other non-antidepressant approaches including cognitive therapy, light therapy, and tryptophan

Topics