Non-randomised trial, 2025
Does Mabelle Cycle help restore regular periods in women with stress-related problems?
Yes, more women taking Mabelle Cycle restored regular periods compared to those in the control group. After three months, 62.5% of those taking Mabelle Cycle had restored cycles versus 27.5% in the control group.
What they did
Researchers divided 80 women aged 18-31 with stress-related period problems into two groups for 3 months. One group (n=40) took Mabelle Cycle supplement. The other (n=40) received psychology consultation and physiotherapy.
What they found
Mabelle Cycle group showed progressive improvement: 22.5% restored cycles after month 1, 50% after month 2, and 62.5% after month 3. The control group showed 7.5%, 17.5%, and 27.5% respectively. Differences were statistically significant from month 2 (p=0.008). The Mabelle Cycle group also showed mood swings reduced from 45% to 7.5%, breast pain reduced from 40% to 10%, and depressive symptoms completely resolved.
What it means for you
A herbal supplement may help restore periods and reduce PMS symptoms in women stressed about their cycles. The study was not randomized and was open-label (participants knew what they were taking), so there may be bias. Results cannot be directly applied to all women with period problems.
62.5%
Mabelle group with restored cycles at month 3
27.5%
Control group with restored cycles at month 3
45% to 7.5%
Mood swings reduction in Mabelle group
About the study
- Original title
- Nonhormonal adjustment of stress-associated menstrual cycle disorders: data of MONARCH trial on the use of Mabelle Cycle complex
- Authors
- Viktor E. Radzinskiy, Mekan R Orazov, Marina Borisovna Khamoshina et al.
- Journal
- Clinical review for general practice
- Year
- 2025
- Study design
- Non-randomised trial
- Participants
- 40
- What was tested
- Mabelle Cycle supplement (2 tablets daily for 3 months) versus psychology consultation and physiotherapy
- Open access
- Yes
- Read the paper
- doi.org/10.47407/kr2025.6.8.00663
Topics
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