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Survey study, 1997

Does pregnancy or the menstrual cycle affect OCD symptoms?

Some women's OCD worsened before their period (42 percent) and after childbirth (29 percent), suggesting hormones may play a role. However, most women's OCD did not change during pregnancy itself (69 percent had no change).

Early or limited evidence 57 women with OCD

What they did

57 women with OCD were interviewed by telephone about how their OCD symptoms changed during the premenstrual phase, during pregnancy, and after childbirth.

What they found

24 women (42 percent) reported their OCD worsened before their period, and 12 (21 percent) described premenstrual dysphoria. Of 38 women who had been pregnant, only 5 (13 percent) had OCD start during pregnancy. Of 29 women with OCD before pregnancy, 20 (69 percent) had no change in symptoms during pregnancy, 5 (17 percent) worsened, and 4 (14 percent) improved. Of 24 women with preexisting OCD who delivered a baby, 7 (29 percent) had worsening after birth. Nine (37 percent) of these 24 also reported postpartum depression.

What it means for you

Some women with OCD experience worsening before their period and after delivery, which suggests hormones may influence the condition. Women with OCD may be at higher risk for postpartum depression. The study was limited because women were asked to recall their symptoms rather than report them at the time they occurred.

57

women with OCD

24 (42%)

premenstrual worsening

7 (29%)

postpartum exacerbation

About the study

Original title
Obsessive-compulsive disorder in pregnancy, the puerperium, and the premenstruum
Authors
Williams KE, Koran LM
Journal
The Journal of clinical psychiatry
Year
1997
Study design
Survey study
Participants
57

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