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Study, 2006

Does paroxetine treat premenstrual dysphoric disorder?

Yes. Paroxetine is an antidepressant medication approved by the FDA and Health Canada for treating PMDD.

Moderate study design Review article (describes PMDD in women of reproductive age).

What they did

Reviewed information about paroxetine and how it fits into treatment guidelines for PMDD, including its approval status.

What they found

PMDD affects 3-8% of women of reproductive age. Symptoms include depressed mood, irritability, anxiety, and physical symptoms that appear during the luteal phase (after ovulation) and go away within 3 days of the period starting. Treatment guidelines recommend lifestyle changes first, then medications. Paroxetine is an antidepressant and was recently approved by the US FDA and Health Canada specifically for PMDD.

What it means for you

If lifestyle changes alone don't relieve your PMDD, paroxetine is an FDA-approved medication option that's recommended as a first-line treatment. This is a review of information, not evidence from a treatment trial.

3-8%

women with PMDD

About the study

Original title
Paroxetine use in the treatment of premenstrual dysphoric disorder
Authors
Misri S, Kendrick K
Journal
Women's health (London, England)
Year
2006
Study design
Study
What was tested
paroxetine for treating PMDD
Open access
Yes

Topics