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Randomised trial, 2004

What medications help control asthma that gets worse around your period?

Several medications may help including leukotriene receptor antagonists, long-acting beta-2 agonists, progesterone, estradiol, and GnRH analogs, but more research is needed to know which works best.

Early or limited evidence Women with premenstrual asthma (review article)

What they did

A review of drug treatments that have been studied for premenstrual asthma. The authors summarized evidence on different medications tested for this condition.

What they found

Several drug therapies may be beneficial: leukotriene receptor antagonists, long-acting inhaled beta-2 agonists, progesterone, estradiol, and gonadotropin-releasing hormone (GnRH) analogs. The authors noted that further double-blind, randomized, placebo-controlled studies are required before the optimal drug therapy can be established.

What it means for you

Asthma that worsens before your period is common and can be treated, but there is no clear first-choice medication yet. Different types of treatments have been tried but need more rigorous study. This is a review of existing research, not a new study, so it shows what has been tried but also identifies gaps in knowledge.

40%

of women affected by premenstrual asthma

About the study

Original title
Premenstrual asthma: emphasis on drug therapy options
Authors
Redmond AM, James AW, Nolan SH et al.
Journal
The Journal of asthma : official journal of the Association for the Care of Asthma
Year
2004
Study design
Randomised trial
What was tested
Various drug therapies reviewed: leukotriene receptor antagonists, long-acting beta-2 agonists, progesterone, estradiol, and GnRH analogs

Topics