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Cohort study, 2023

Are premenstrual disorders linked to depression, anxiety, and self-harm in teenage girls?

Yes. Girls with premenstrual disorders have 4 to 7 times higher rates of depression, anxiety, self-injury, and suicide risk compared to boys and girls without the disorder. This suggests premenstrual disorders may cause much of the difference in mental health problems between teenage boys and girls.

Moderate study design 21,239 adolescents aged 10-19 in China (10,563 girls) from the Santai Youth Mental Health Promotion Cohort

What they did

Cross-sectional survey of 21,239 people aged 10-19 in China. Researchers asked about premenstrual disorders, depression, anxiety, history of self-injury, and suicide risk using standard questionnaires.

What they found

Girls with premenstrual disorders had 4.76 times higher depression, 3.86 times higher anxiety, 4.70 times higher self-injury rates, and 7.49 times higher suicide risk. Girls without premenstrual disorders had rates similar to boys.

What it means for you

Premenstrual disorders appear to be strongly linked to mental health problems in teenage girls. A main limitation is that girls with premenstrual disorders may have reported higher depression and anxiety symptoms partly because these symptoms naturally overlap with PMS symptoms.

4.76

times higher depression in girls with premenstrual disorders

7.49

times higher suicide risk in girls with premenstrual disorders

10,563

girls studied

About the study

Original title
Premenstrual disorders and gender differences in adolescent mental health
Authors
Li Y, Jiang J, Halldorsdottir T et al.
Journal
Journal of affective disorders
Year
2023
Study design
Cohort study
What was tested
None - this was an observational study

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