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Review, 2004

What is PMDD and how is it treated?

PMDD is a severe form of PMS with physical and behavioral symptoms during the second half of the menstrual cycle. Treatment starts with lifestyle changes and over-the-counter medications, and includes antidepressants if needed.

Strong study design PMDD diagnosis and management in clinical practice

What they did

Reviewed clinical knowledge and research on PMDD diagnosis, causes, and treatment approaches.

What they found

PMDD results from interactions between brain chemicals and menstrual hormones. Treatment options include lifestyle changes, over-the-counter medications, and selective serotonin reuptake inhibitors. Doctors should be cautious about alternative therapies promoted in the media.

What it means for you

Doctors have a stepwise approach to treating PMDD, starting with lifestyle and over-the-counter options before moving to antidepressants. Many alternative therapies lack rigorous evidence.

About the study

Original title
Premenstrual dysphoric disorder: a review for the treating practitioner
Authors
Kaur G, Gonsalves L, Thacker HL
Journal
Cleveland Clinic journal of medicine
Year
2004
Study design
Review
What was tested
Review of PMDD management

Topics