Case report, 2007
How does sertraline affect thinking in women with PMDD?
One female aviator with PMDD received sertraline 25 mg daily for 5-7 days per month and had her thinking and attention assessed while on and off the medication. The report interprets her neuropsychological performance and discusses potential cognitive effects.
What they did
Tested one female aviator with PMDD on two occasions: once while taking sertraline 25 mg daily for 5-7 days per month, and once while not taking it. Both tests were on day 6 of her menstrual cycle. She also had a blinded flight evaluation by a pilot both times.
What they found
The report interprets her thinking and attention while on and off sertraline and discusses how this relates to her ability to fly safely.
What it means for you
This case examined a female pilot's thinking and flight safety while on and off sertraline for PMDD. As a single case, it can only describe one person's experience, not what would happen for others.
25 mg
daily sertraline dose
5-7
days per month of medication
About the study
- Original title
- Premenstrual dysphoric disorder: treatment with sertraline, neuropsychological effects, and flight status
- Authors
- Kratz K, Anderson S, Poppen B
- Journal
- Aviation, space, and environmental medicine
- Year
- 2007
- Study design
- Case report
- What was tested
- Sertraline 25 mg daily for 5-7 days per month
- Read the paper
- https://pubmed.ncbi.nlm.nih.gov/17547314/
Topics
Related studies
Review, 2024
What are the most effective treatments for PMDD?
Systematic review, 2024
Do SSRI antidepressants help treat PMS and PMDD?
Review, 2017
What causes PMDD and what are the best treatments?
Review, 2015
What do we know about PMS and PMDD and how are they treated?
Systematic review, 2012
How effective are cognitive-behavioral therapy and antidepressants for PMS and PMDD?
Review, 2011
What are PMS and PMDD, and how common are they?