Study, 1990
Can the antidepressant amitriptyline help PMS?
Yes, in this small family study, seven women with PMS felt better after taking amitriptyline. The results suggest PMS might run in families, especially when depression is involved, but more research is needed.
What they did
A researcher identified 11 family members across three generations who had premenstrual complaints. Seven of them met the definition of PMS. Those seven were treated with amitriptyline.
What they found
Seven women treated with amitriptyline improved.
What it means for you
This is a very small case study of just one family. It suggests amitriptyline might help PMS and that genetics may play a role, but we need larger studies to be sure. The main limit is that it involves only one family and a small number of people.
11
family members studied
7
women with PMS who were treated
3
generations in the family
About the study
- Original title
- Premenstrual syndrome in three generations responds to antidepressants
- Authors
- Taghavi E
- Journal
- The Australian and New Zealand journal of psychiatry
- Year
- 1990
- Study design
- Study
- Participants
- 11
- What was tested
- Amitriptyline, an antidepressant
- Read the paper
- doi.org/10.3109/00048679009077693
Topics
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