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Survey study, 2025

Are premenstrual symptoms linked to depression in teenage girls?

Yes. Girls with premenstrual symptoms were about 1.7 times more likely to have depressive symptoms than girls without PMS.

Moderate study design 2970 Korean adolescent girls aged 14-17 who had started menstruation

What they did

Large nationwide cross-sectional survey in Korea with 2970 adolescent girls aged 14-17 who had started menstruation. Researchers assessed premenstrual symptoms and depressive symptoms using standard questionnaires.

What they found

70.5% reported premenstrual symptoms. The most common PMS symptoms were irritability in 43.8%, abdominal bloating in 32.8%, and breast tenderness in 27.5%. 15.5% had depressive symptoms. Girls with premenstrual symptoms were about 1.7 times more likely to have depressive symptoms. Satisfaction with body image was linked to depression, but body weight was not.

What it means for you

Premenstrual symptoms in teenage girls are clearly linked to depression. Doctors should ask about both PMS and depression when caring for teenagers. This was a large nationwide study, but findings may not apply to girls in other countries.

70.5%

girls with premenstrual symptoms

15.5%

girls with depressive symptoms

1.7 times

increased likelihood of depression with PMS

About the study

Original title
Prevalence of premenstrual syndrome and its relationship to depression among Korean adolescents: A nationwide cross-sectional study
Authors
Lee H, Choi KS, Rhee Y
Journal
Taiwanese journal of obstetrics & gynecology
Year
2025
Study design
Survey study
Participants
3,000
What was tested
None
Open access
Yes
Original abstract

Objective: To investigate the prevalence of PMS and depressive symptoms and to determine their association among Korean adolescent girls using a nationally representative cross-sectional survey. Materials and methods: The Korean Study of Women's Health Related Issues (K-Stori)was used. Of the 3000 adolescent girls aged 14-17 years, the study subjects were 2970 girls after menarche. Depressive symptom was assessed with the PHQ-9. Multivariable logistic regression analysis was used to investigate factors associated with depressive symptom. Results: The prevalence of PMS was 70.5 %. Irritability (43.8 %), abdominal bloating (32.8 %), and breast tenderness (27.5 %) were the most predominant symptoms. The prevalence of depressive symptom was 15.5 %. Girls with PMS were more likely to be depressed than those who did not experience PMS (OR, 1.70; CI, 1.31-2.20). BMI was not associated with depressive symptom. However, a significant association was noted between satisfaction with one's body image and depressive symptom. Ever-smokers were more likely to be depressed than never-smokers (OR, 1.64; CI, 1.10-2.45). Conclusions: PMS were significantly associated with depressive symptom. PMS should be taken into account in the management of depression. Our study emphasized the significance of a multidisciplinary approach.

Reproduced under CC-BY.

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