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Randomised trial, 2011

Is Vitex agnus castus effective for premenstrual dysphoric disorder?

Vitex agnus castus appeared to reduce PMDD symptoms with no reported side effects. However, this was a very small preliminary study without clear methodology or statistical comparison, so firm conclusions cannot be drawn.

Early or limited evidence Women with PMDD (sample size not clearly specified)

What they did

Clinical study comparing women with PMDD treated with Vitex agnus castus to results from a separate group treated with fluoxetine. The abstract does not clearly describe the number of participants, duration, dosage, or study design.

What they found

Treatment with Vitex agnus castus was effective for PMDD with no side effects reported. The authors suggest results were comparable to fluoxetine treatment, although specific numbers and statistical comparison are not provided in the abstract.

What it means for you

Vitex agnus castus may be helpful for PMDD, but this is a very preliminary study. The main limitations are unclear sample size, lack of statistical comparison between treatments, and limited information about methodology. Much larger, well-designed studies are needed.

effective

reported outcome with Vitex

About the study

Original title
[Psychic aspects of the premenstrual dysphoric disorders. New therapeutic strategies: our experience with Vitex agnus castus]
Authors
Ciotta L, Pagano I, Stracquadanio M et al.
Journal
Minerva ginecologica
Year
2011
Study design
Randomised trial
What was tested
Vitex agnus castus (dosage and duration not clearly specified)

Topics