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Survey study, 2021

Do girls with PMS have different estrogen levels than those without?

Girls with PMS had higher estrogen levels than those without. Girls with severe PMS had the highest levels. This is a one-time measurement, so we cannot tell if high estrogen causes PMS.

Early or limited evidence 50 teenage girls (25 with PMS, 25 without) at Pesantren Darul Arqam, Makassar

What they did

Researchers compared 25 teenage girls with PMS to 25 without PMS. Girls with PMS kept daily symptom diaries and provided blood samples. Estrogen was measured using a lab test called ELISA. The study lasted 3 months.

What they found

The mean estrogen level in girls with PMS was 148.32 pg/ml, compared to 98.00 pg/ml in girls without PMS. Girls with mild PMS had 130.73 pg/ml and those with severe PMS had 162.14 pg/ml. The difference was significant.

What it means for you

Higher estrogen is linked to PMS in teenage girls, and severe PMS is linked to even higher estrogen. The study measured estrogen only once, so we don't know if this changes through the cycle or if high estrogen actually causes PMS.

148.32

mean estrogen level in girls with PMS (pg/ml)

98.00

mean estrogen level in girls without PMS (pg/ml)

162.14

mean estrogen level in girls with severe PMS (pg/ml)

About the study

Original title
The effect of estrogen hormone on premenstrual syndrome (PMS) occurrences in teenage girls at Pesantren Darul Arqam Makassar
Authors
Noviyanti NI, Gusriani, Ruqaiyah et al.
Journal
Gaceta sanitaria
Year
2021
Study design
Survey study
What was tested
None; this was an observational measurement study.
Open access
Yes

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