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Randomised trial, 1998

Does Vitex agnus castus help cyclical breast pain?

Yes. The extract reduced breast pain faster than placebo and was well tolerated.

Moderate study design 97 women with breast pain for at least 5 days of their menstrual cycle

What they did

In a double-blind, placebo-controlled study, 97 women with cyclical breast pain were randomly assigned to Vitex agnus castus extract or placebo. Women took either the extract (1.8 ml daily in two 30-drop doses) or placebo pills daily for 3 consecutive menstrual cycles. Pain was measured on a visual pain scale.

What they found

Breast pain intensity decreased more quickly in the Vitex group than the placebo group. The extract had satisfactory tolerability with few side effects reported.

What it means for you

Vitex may help reduce cyclical breast pain faster than placebo. The main limits are that the abstract does not specify how much pain reduction occurred or give statistical significance, and the sample size is relatively small.

97

Women in the study

3

Menstrual cycles of treatment

1.8 ml

Daily dose of Vitex

About the study

Original title
[Treatment of cyclical mastodynia using an extract of Vitex agnus castus: results of a double-blind comparison with a placebo]
Authors
Halaska M, Raus K, Bĕles P et al.
Journal
Ceska gynekologie
Year
1998
Study design
Randomised trial
Participants
49
What was tested
Vitex agnus castus 1.8 ml daily

Topics