Case-control study, 1992
Does a depression-related blood marker change during the menstrual cycle?
No, the study found no clear relationship between this blood marker and menstrual cycle phase, PMS symptoms, or hormone levels in healthy women.
What they did
Study of healthy young women measuring a blood marker related to depression during different phases of their menstrual cycle. Researchers looked for relationships between the marker level, menstrual cycle phase, PMS symptoms, and hormone levels (progesterone and estradiol).
What they found
No significant relationship was found between the blood marker and the phase of the menstrual cycle, PMS symptoms, progesterone level, or estradiol level.
What it means for you
This blood marker doesn't change with the menstrual cycle in healthy women. However, the study only included healthy women without PMS, so findings might differ in women who have PMS. The study was conducted in a limited population, so we should be cautious about generalizing these results.
About the study
- Original title
- Variation in platelet [3H]imipramine binding during the menstrual cycle in healthy young women
- Authors
- Peter M. Ellis, C. Joy McIntosh, Russell R. Cooke
- Journal
- Human Psychopharmacology Clinical and Experimental
- Year
- 1992
- Study design
- Case-control study
- What was tested
- None - observational study
- Read the paper
- doi.org/10.1002/hup.470070107
Topics
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