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Review, 2007

What is PMS and what treatments work?

PMS affects an estimated 75% of women during the luteal phase of their cycle. Diagnosis is based on symptom tracking, not blood tests. Calcium supplements and SSRIs are treatments with excellent evidence for reducing symptoms.

Moderate study design Review article applicable to women of childbearing age

What they did

Review of scientific literature on PMS diagnosis, causes, and treatment options.

What they found

PMS is a recurrent disorder occurring in the luteal phase, characterized by physical, psychological, and behavioral changes. No tests can confirm it; diagnosis requires daily symptom tracking. Symptoms remit with the onset of menstruation. The cause is likely abnormal responses to normal hormone fluctuations. Both non-drug and drug treatments exist. Calcium carbonate and selective serotonin reuptake inhibitors (SSRIs) have demonstrated excellent efficacy.

What it means for you

PMS is common and treatable. Women should track symptoms for an accurate diagnosis. While lifestyle changes are tried first, medications are available if needed. This is a review article summarizing existing evidence rather than new research.

75%

Estimated percentage of women affected by PMS

2

Treatments with excellent evidence (calcium, SSRIs)

About the study

Original title
[An overview of premenstrual syndrome]
Authors
Zaafrane F, Faleh R, Melki W et al.
Journal
Journal de gynecologie, obstetrique et biologie de la reproduction
Year
2007
Study design
Review
What was tested
Various treatments reviewed

Topics