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Randomised trial, 2014

Is chamomile extract more effective than mefenamic acid for premenstrual syndrome?

Yes, for emotional symptoms. Chamomile reduced emotional symptoms by about 30 to 33 percent while mefenamic acid reduced them by about 11 percent.

Moderate study design 90 students living in dormitories in Iran with premenstrual syndrome

What they did

A randomized double-blind trial with 90 students living in dormitories in Iran. Women filled daily forms for 2 months to confirm PMS diagnosis. Then they received either chamomile 100mg or mefenamic acid 250mg three times daily for 2 menstrual cycles.

What they found

Emotional symptom reduction was 30.1 ± 26.6 and 33.4 ± 25.3 percent in the chamomile group compared to 11.6 ± 25.7 and 10.7 ± 26.8 percent in the mefenamic acid group after two cycles of treatment.

What it means for you

Chamomile may work better than mefenamic acid for emotional symptoms specifically. However, the study only measured emotional relief and was limited to Iranian students.

90

students in study

100mg

chamomile dose per dose

250mg

mefenamic acid dose per dose

About the study

Original title
Comparison of the effects of Matricaria chamomila (Chamomile) extract and mefenamic acid on the intensity of premenstrual syndrome
Authors
Sharifi F, Simbar M, Mojab F et al.
Journal
Complementary therapies in clinical practice
Year
2014
Study design
Randomised trial
Participants
90
What was tested
Chamomile extract 100mg three times daily or mefenamic acid 250mg three times daily for 2 menstrual cycles

Topics