Cohort study, 1994
Do women with PMS have lower magnesium levels?
Yes, women with PMS have lower magnesium in their red blood cells. This difference appears throughout the menstrual cycle, not just before the period.
What they did
26 women with PMS and 19 control women had their blood magnesium measured several times across their menstrual cycle, including plasma, red blood cells, and other blood cells.
What they found
Women with PMS had significantly lower magnesium concentrations in red blood cells and other blood cells at each measurement time.
What it means for you
Women with PMS may have lower magnesium overall, but the study was small and did not test whether supplementing magnesium would help.
26
Women with PMS
19
Control women
About the study
- Original title
- Magnesium measures across the menstrual cycle in premenstrual syndrome
- Authors
- Rosenstein DL, Elin RJ, Hosseini JM et al.
- Journal
- Biological psychiatry
- Year
- 1994
- Study design
- Cohort study
- Participants
- 26
- What was tested
- None
- Read the paper
- doi.org/10.1016/0006-3223(94)90103-1
Topics
Related studies
Cohort study, 2020
Are calcium and magnesium levels lower in women with PMS?
Randomised trial, 2000
What non-antidepressant treatments might help PMS?
Randomised trial, 2025
Does dark chocolate help exercise performance and muscle pain during the premenstrual phase?
Study, 2025
Could ginkgo biloba, soy, and other nutrients help hormone-related mood problems like PMS and PMDD?
Study, 2025
Could taking a combination of vitamins and minerals help with PMS and PMDD symptoms?
Case-control study, 2015
Are vitamin D, calcium, and magnesium linked to PMS?