Skip to content

Randomised trial, 1983

Which nutritional supplements help treat premenstrual syndrome?

Vitamin B6 at 40-100 mg twice daily is widely used for PMS, especially in milder cases. Evening primrose oil at 2-3 g per day shows encouraging early results. Other nutritional approaches may help but are unlikely to provide complete relief alone.

Early or limited evidence Review paper, not original research

What they did

This is a review paper that examined non-drug nutritional approaches to treating PMS, including their doses and how they work.

What they found

Vitamin B6 (pyridoxine) at 40-100 mg twice daily is widely used to treat PMS in less severe cases. Evening primrose oil at 2-3 g per day (the source of gamma-linolenic acid) has shown encouraging preliminary results, though a double-blind placebo-controlled study was still in progress. Some evidence suggests allergies may worsen premenstrually, so avoiding trigger substances may help.

What it means for you

Vitamin B6 and evening primrose oil are potential non-drug treatments for PMS, but evidence is still limited and more research is needed. Nutritional approaches alone are unlikely to provide complete relief, especially for severe PMS.

40-100 mg

Vitamin B6 dose, twice daily

2-3 g

Evening primrose oil per day

About the study

Original title
Nutritional Approaches to the Treatment of Premenstrual Syndrome
Authors
M. G. Brush
Journal
Nutrition and Health
Year
1983
Study design
Randomised trial
What was tested
Vitamin B6 at 40-100 mg twice daily and evening primrose oil at 2-3 g per day

Topics