Randomised trial, 2000
Which dietary supplements help PMS?
Only calcium has strong evidence from large rigorous trials. Magnesium, vitamin E, and carbohydrate supplements show limited promise but need more research. Vitamin B6 and evening primrose oil have mixed results.
What they did
Review of published research on dietary supplements for PMS. The authors examined available evidence from clinical trials.
What they found
Calcium is the only supplement proven effective in a large double-blind placebo-controlled trial. Magnesium, vitamin E, and carbohydrate supplements might help but need more research. Vitamin B6 trials show conflicting results and high doses can cause nerve damage. Evening primrose oil showed no benefit in the most rigorous studies. Herbal products lack consistent evidence.
What it means for you
If you want to try a supplement, calcium has the best evidence. Others need more research. High-dose vitamin B6 can be harmful. Herbal products are not yet supported by solid science. Limitation: This review examines existing studies which vary in quality.
calcium
only supplement with strong evidence
vitamin B6
conflicting results, can cause nerve damage
primrose oil
no benefit in rigorous studies
About the study
- Original title
- The potential for dietary supplements to reduce premenstrual syndrome (PMS) symptoms
- Authors
- Bendich A
- Journal
- Journal of the American College of Nutrition
- Year
- 2000
- Study design
- Randomised trial
- What was tested
- Various dietary supplements: calcium, magnesium, vitamin E, vitamin B6, evening primrose oil, and herbs
- Read the paper
- doi.org/10.1080/07315724.2000.10718907
Topics
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