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Study, 2020

Can ozone therapy reduce PMS symptoms?

In 5 women with PMS, inflammation markers decreased and infections were reduced with ozone therapy combined with diet changes. Women reported improvement.

Early or limited evidence 5 women with PMS attending a clinic between October 2018 and August 2019

What they did

5 women with PMS were treated with ozone therapy (rectal, uterine, and cervical applications) plus an anti-inflammatory diet and supplements between October 2018 and August 2019. Inflammation markers and infections in the genital area were measured at the start, middle, and end of treatment.

What they found

Two inflammation markers in the uterus decreased in all 5 women (100%), indicating reduced inflammation and clinical improvement. Intestinal infections (Candida and gram-negative bacteria) found in the genital area were also reduced.

What it means for you

This suggests ozone therapy might reduce uterine inflammation and infection. Main limitations: only 5 women studied, no comparison group, and the researchers say more trials are needed.

5

women treated

100%

showed decreased inflammation markers

About the study

Original title
Ozonoterapia en el abordaje integrativo del síndrome premenstrual. Reporte de casos
Authors
Alejandra Menassa de Lucía
Journal
Ozone Therapy Global Journal
Year
2020
Study design
Study
Participants
5
What was tested
Ozone therapy (rectal, uterine, and cervical applications) plus anti-inflammatory diet and supplements
Open access
Yes

Topics