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Case report, 1987

Can women with premenstrual mood changes develop serious mood disorders?

In some women with premenstrual mood changes, a serious mood disorder called manic-depressive illness may develop, but mainly in those with genetic predisposition. Doctors should watch for severe mood problems after pregnancy in women with this pattern.

Early or limited evidence 3 women with premenstrual mood changes who developed manic-depressive illness

What they did

Described 3 women who had mood swings tied to their menstrual cycle and then developed manic-depressive illness that required intensive psychiatric treatment or hospital admission.

What they found

All 3 women had a pattern of mood changes during their menstrual cycle, followed by development of manic-depressive illness.

What it means for you

Women with premenstrual mood swings might be at risk of developing manic-depressive illness if they have the genetic background for it. The main limitation is that this comes from just 3 cases, so we don't know how common this pattern is.

About the study

Original title
Premenstrual mood changes in affective disorders
Authors
Ghadirian AM, Kamaraju LS
Journal
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne
Year
1987
Study design
Case report
What was tested
None
Open access
Yes

Topics