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Interview study, 2025

What causes PMS and PMDD?

PMS and PMDD involve hormonal changes (estrogen and progesterone), but they also depend on how women think, feel, and experience their social world. Understanding all three together gives a fuller picture than focusing only on hormones.

Early or limited evidence A review of published research (not a study of women with PMS or PMDD).

What they did

Reviewed and summarized research on PMS and PMDD from multiple studies using a framework that considers biological, psychological, and social factors together.

What they found

The main biological cause is the rise and fall of estrogen and progesterone during the cycle. However, how women think, their emotional state, stress, relationships, and social pressures also shape whether and how much someone experiences PMS or PMDD symptoms. Recent research supports looking at all three factors together, not just hormones alone.

What it means for you

PMS and PMDD are complex. Treatments and support might work better if doctors and support systems look at hormones, mental health, stress, relationships, and social pressures together rather than focusing only on biology. This review did not test any treatments, so it cannot say which approaches work best.

About the study

Original title
Understanding PMS and PMDD: The Role of Body, Mind, and Society
Authors
Shivani Yadav
Journal
International Journal for Research in Applied Science and Engineering Technology
Year
2025
Study design
Interview study
What was tested
None - a review of existing knowledge.
Open access
Yes

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