Completed
Stress & Premenstrual Symptoms Study
Psychophysiology, Neurosteroids, and Stress in Premenstrual Dysphoric Disorder
- Status
- Completed
- Registry ID
- NCT02777372
- Type
- Interventional (tests a treatment)
- Phase
- Phase 4
- Conditions
- PMDD, Stress, Mood
- What is tested
- Sertraline (drug)
- Sponsor
- Johns Hopkins University
- Where
- United States
- Participants
- 84
- Start
- 2016-04-01
- Completion
- 2021-12-01
- Last update
- 2025-06-12
- Results posted
- Yes
About the study
This study that aims to evaluate the psychophysiology of premenstrual mood disorders (PMDs) at baseline and after treatment with sertraline. Participants will include women with PMDs and healthy female controls. Participation involves a baseline visit to determine eligibility and three study visits that include questionnaires and stress reactivity assessment via an acoustic startle paradigm. Female participants with PMDs will receive sertraline during the premenstrual phase.
Summary from ClinicalTrials.gov.